Exercise 1: Redoing the Base Rate Math With a Rarer Disease — Possible Solution ================================================================================== Out of 10,000 people, 1 in 10,000 have the disease, so exactly 1 person actually has it. The remaining 9,999 people are healthy. With a 5% false positive rate applied to those 9,999 healthy people: 9,999 x 0.05 = approximately 500 false positives (499.95, rounding to 500 for a whole number of people). Total positive results = 1 true positive + 500 false positives = 501 total positive results. Percentage of positives that are real (true positive rate among positives) = 1 / 501 = approximately 0.2%. ANSWER: Out of 10,000 people, there would be approximately 501 total positive results (1 true positive + about 500 false positives), and only about 0.2% of those positive results would actually reflect a real case of the disease - an even smaller real percentage than the chapter's own 1-in-1,000 example, because the rarer the underlying disease, the more the false positives from an imperfect test dominate the pool of positive results. WHY THIS WORKS AS AN ANSWER ------------------------------ This correctly redoes the chapter's own real calculation with the new numbers, showing the same step-by-step reasoning (true positives vs. false positives among the healthy population) applied to a rarer condition.